Chest-pain triage
Supports rapid assessment when patients present with possible AMI and laboratory turnaround time is critical.
IVD / Cardiac Marker
Myoglobin / CK-MB / Troponin I Rapid Test
A professional-use lateral flow panel for qualitative detection of three key cardiac injury markers from whole blood, serum, or plasma.
3 markers / 1 cassette15-minute resultProfessional use only
Product Overview
Rapid multi-marker support for suspected acute myocardial infarction.
The Myoglobin / CK-MB / Troponin I Rapid Test is a lateral flow immunoassay for qualitative detection of myoglobin, creatine kinase MB, and cardiac troponin I. It is intended for professional in vitro diagnostic use as an aid in assessment of suspected acute myocardial infarction.
15 minRead time
3Cardiac markers
WB / S / PSpecimen types
IVDProfessional use
Medical Background
Why three markers matter
Acute myocardial infarction causes cardiomyocyte necrosis. As cell membranes lose integrity, intracellular proteins enter circulation in a time-dependent sequence. A combined panel helps providers see early, mid, and sustained marker windows in one test.
MyoglobinEarly marker. First rise around 1-3 hours; peaks around 4-8 hours; usually returns toward baseline within 12-24 hours.
CK-MBIntermediate marker. Rises around 4-6 hours; peaks at 12-24 hours; may remain elevated for 36-48 hours.
Troponin ICardiac-specific injury marker. Rises around 4-6 hours and can remain elevated for 7-14 days.
Cardiac marker kinetics after AMI onset
Myoglobin contributes early sensitivity, CK-MB supports the diagnostic window, and troponin I remains useful later after symptom onset.
Clinical Use
Where the panel fits in provider workflows
Point-of-care support
Whole blood compatibility allows testing closer to patient care while serum or plasma can be used in laboratory settings.
Broader marker coverage
Combines early, intermediate, and sustained markers so providers can interpret results in relation to symptom timing.
Procedure & Results
Simple cassette workflow
1Prepare
Bring cassette and specimen to room temperature, 15-30 C. Remove cassette from sealed pouch and place on a level surface.
2Add specimen
Serum/plasma: add 3 drops, about 100 uL. Whole blood: add 2 drops, about 70 uL, then 1 drop buffer.
3Run test
Start timer immediately after adding sample and buffer.
4Read
Interpret at 15 minutes. Do not read after 20 minutes.
Positive
MKTC
Control line plus one or more marker test lines appear. Report the visible marker line(s) as reactive at or above cutoff.
Negative
MKTC
Only the control line appears. Marker levels are below cutoffs. This does not exclude AMI when clinical suspicion remains high.
Invalid
MKTC
No control line appears. Repeat with a new cassette and review specimen volume and procedure.
Specimen Handling
Use clear, properly handled specimens
Specimen typesHuman whole blood, serum, or plasma.
Whole bloodCollect venous whole blood in EDTA or heparin tube. Store at 2-8 C for up to 5 days. Do not freeze whole blood.
Serum / plasmaSeparate as soon as possible to avoid hemolysis. Store at 2-8 C for up to 7 days, or at -20 C for longer storage.
AvoidGrossly hemolyzed, lipemic, or turbid samples, as these may interfere with interpretation.
Detection cutoffs
| Marker | Cutoff | Normal range |
|---|---|---|
| Troponin I | >= 0.5 ng/mL | < 0.5 ng/mL |
| CK-MB | >= 5 ng/mL | < 5 ng/mL |
| Myoglobin | >= 50 ng/mL | 30-90 ng/mL |
Qualitative test: line intensity does not correlate with concentration.
Specifications
Product information from leaflet and IFU
Product nameMyoglobin / CK-MB / Troponin I Rapid Test
FormatCassette, 25 tests per box
Intended useQualitative detection of myoglobin, CK-MB, and cardiac troponin I in human whole blood, serum, or plasma; aid in suspected AMI assessment
MethodSandwich lateral flow immunochromatographic assay
SpecimenWhole blood, serum, or plasma
Read time15 minutes; do not read after 20 minutes
Storage4-30 C in sealed pouch; protect from sunlight, moisture, and heat
After openingUse within 1 hour
ComponentsTest cassette, dropper, buffer vial, desiccant, IFU; single use only
Use settingProfessional and in vitro diagnostic use only
Performance
Leaflet performance: cTnI sensitivity 99.09%, specificity 98.95%, accuracy 99.00%; CK-MB sensitivity 97.87%, specificity 99.03%, accuracy 98.67%; myoglobin sensitivity 97.62%, specificity 99.31%, accuracy 98.83%.
Warnings
For professional IVD use only. Do not reuse. Do not use if pouch is damaged or expired. Follow specimen handling precautions and treat all clinical samples as potentially infectious.
Clinical limitation
Results should be interpreted with symptoms, ECG, clinical history, and other diagnostic findings. A negative rapid test does not independently rule out myocardial infarction.